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Tamoxifen-treated TPO-creER;Braf V600E /p53 -/- transgenic mice, which exhibit ATC features including shortened survival and histologic morphology, also revealed high level of one-carbon metabolism genes such as PHGDH , SHMT2 , MTHFD2 , MTHFD1L , PSAT1, and PSPH compared to PTC mice despite different tendency with human (Fig
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