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and a multifunctional docking site (MFDS), which recruits downstream signaling molecules and adapter proteins including SHP2, growth factor receptor-bound protein 2 (GRB2), GRB2-associated binding protein 1 (GAB1), and phosphatidylinositol 3-kinase (PI3K), upon the phosphorylation of Y1349 and Y1356 40,41 (Fig
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