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Phase I/IIa, first-in-human (FIH), open-label, dose escalation trial with expansion cohorts to evaluate safety and preliminary efficacy of CLDN6 CAR-T with or without CLDN6 RNA-LPX in patients with CLDN6-positive relapsed or refractory advanced solid tumors
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Additionally, intestinal epithelial cells can import intact GSH from the lumen via specific plasma membrane transporters ( FIGURE 3 FIGURE 4 Glutathione cellular distribution Glutathione is found in almost all cellular compartments, including the nucleus (54, 64–68) (Figures 2, 4)
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