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Considering that GSH is not homogenously distributed and that oligodendrocytes have relatively low levels of GSH and high levels of iron, making them more vulnerable to oxidative stress (Rae and Williams, 2017), we could speculate that the lower GSH level observed in our cohort of post COVID-patients could facilitate damages to the WM microstructure and explain the association between GSH depletion and increased WMHs
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