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Short-Term Clinical Results of Single-Injection Autologous Bone Marrow Aspirate Concentrate (BMAC) as a Therapeutic Option/Tool in Knee Osteoarthritis

Supplementary material The Supplementary Material for this article can be found online at: Glossary AMPK AMP-activated Protein Kinase APAF-1 Apoptotic peptidase-activating factor 1 Bax BCL2-Associated X protein Bcl-2 B-cell lymphoma/leukemia-2 Caspases Cysteine-requiring aspartate protease CCNE1 Cyclin E1 DED Death effector domain DISC Death-inducing signaling complex EMs Endometriosis ER Endoplasmic reticulum ERK1/2 Extracellular signal-regulated kinase 1/2 FADD Fas-associated death domain FTH1 Ferritin Heavy Chain 1 FTL Ferritin Light Chain FOX Forkhead box GM-CSF Granulocyte-macrophage colony-stimulating factor GSK-3β Glycogen synthase kinase 3β GPX4 Glutathione Peroxidase 4 HNF-1β Hepatocyte Nuclear Factor 1 beta HO-1 Heme Oxygenase-1 IhOESCs Immortalized human ovarian endometriotic stromal cell lines LC3 Microtubule-associated Protein Light Chain 3 MAPK Mitogen-activated protein kinase MDA Malondialdehyde MLKL Mixed lineage kinase domain-like pseudokinase MMP-9 Matrix metalloproteinase-9 mTOR mammalian target of rapamycin NF-κB Nuclear Factor kappa-B NOX4 Nicotinamide Adenine Dinucleotide Phosphate Oxidase 4 NRF2 Nuclear factor erythroid 2-related factor 2 NQO1 Quinone Oxidoreductase 1 PAINS Pan-assay interference compoundss PCNA Proliferating Cell Nuclear Antigen PGC-1α Peroxisome proliferator-activated receptor-γ coactivator-1α PI3K/AKT Phosphoinositide 3-kinase/Protein Kinase B RIPK Receptor-interacting protein kinase ROS Reactive oxygen species SMAC Second Mitochondrial Activator of Caspases TGF-β1 Transforming Growth Factor Beta Receptor I References 1 AgicA.DjalaliS.DiedrichK.HornungD

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These hormonal fluctuations can manifest in various ways on the skin