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However, during the same 10-year period in the United States, the death rate of CRC increased by 1.3% annually in individuals younger than 50 years of age (3)

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As is the case with the oxidative phase, the non-oxidative phase can be divided into 4 main stages/steps that include: Step 1 - During the first stage of the non-oxidative phase, there are two main reactions that ultimately result in the production of xylulose 5-phosphate