glutathione lung peroxidase 3 localizes to the epithelial lining fluid and the extracellular matrix in interstitial disease Select Your Color Here:Dark Pink

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The failure to see changes in SPCA1 expression are likely due to a timing difference (30 days as compared to 6 hours) or in vivo/in vitro differences, but what can be observed is that SPCA1 can be oversaturated by Mn, and toxicity will result from presumably blocking normal Ca 2+ sequestration