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TRANSLATING THE BIOLOGY OF AGING INTO NEW THERAPEUTICS FOR ALZHEIMER'S DISEASE: SENOLYTICS • The Journal of Prevention of Alzheimer's Disease
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While the mechanisms underlying LPS-mediated reduction in BBB integrity and microglial activation are not well defined, peripheral exposure of mice to LPS was shown to induce rapid activation of endothelial NF-kB through TLR4 stimulation
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