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The evaluation of the anticancer activity of compound 41 revealed it induced apoptosis in both HCT-116 (GI 50 = 2.29 μM) and breast cancer cell line MDA-MB-231 (GI 50 = 2.63 μM) cell lines, but also caused a G2/M phase cell cycle arrest in HCT-116 cells
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These findings are also in parallel with the larger paradigm of the global neuroinflammatory effects of chronic stress proceeding TBI
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