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Although oral GSH supplementation has poor bioavailability [4], N-Acetyl Cysteine (NAC) has been shown to successfully raise plasma glutathione levels in those with schizophrenia [5]”
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In addition, curcumin is able to induce detoxifying enzymes by up-regulating the Kelch-like ECH-associated protein 1 (Keap1)/Nrf2/ARE pathway and it is able to down-regulate NF-kB and the expression and concentration of proinflammatory cytokines by preventing the damaging effects in the liver caused by HMs [84]
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